Danielle Karber , CNP
Nurse Practitioner β’ Sioux Falls, SD
1301 W 18th St
Sioux Falls, SD 571050401
This profile restates public CMS/NPPES data; T-MedInfo gives no medical advice — consult a licensed professional, and call 911 for emergencies.
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Danielle Karber is listed in NPPES under Nurse Practitioner.
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NPI assigned on September 9, 2021; this date does not establish years in practice.
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Published CMS data list 11 Medicare Part D prescriptions, including refills, in 2024.
Source: CMS, Medicare Part D Prescribers β by Provider and Drug, 2024. Published rows only; this is not a quality measure.
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Published Part D records, 2024:
- Lisinopril β 11 prescription fills, including refills.
Source: CMS, Medicare Part D Prescribers β by Provider and Drug, 2024. Drug names come from pharmacy claims. Listing a drug here is not an endorsement or a recommendation.
See the full table Β· Guide: How to read Medicare Part D prescriber data
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Fewer Part D prescriptions than 95% of clinicians listed under Nurse Practitioner in Sioux Falls, SD (2024, 143 clinicians with data). Median for this group: 359. Middle half: 68 to 1,118.
Fewer Part D prescriptions than 95% of clinicians listed under Nurse Practitioner in South Dakota (2024, 285 clinicians with data). Median for this group: 349. Middle half: 78 to 1,193.
Source: CMS, Medicare Part D Prescribers β by Provider and Drug, 2024. Billing and prescribing volume is not a quality rating.
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Medicare Part D prescriptions went from 11 in 2022 to 11 in 2024.
Source: CMS, Medicare Part D Prescribers β by Provider and Drug, 2022β2024.
Practice Location & Contact Primary Location
1301 W 18th St
Sioux Falls, SD 571050401
Matched by practice address or phone in NPPES. A shared address or phone does not confirm that this clinician works there.
NPPES lists 3 distinct additional practice-address records in Chamberlain, SD; Sioux Falls, SD; Watertown, SD. See the list
Source: CMS NPPES NPI Registry, practice location records; release date unavailable.
CMS Doctors and Clinicians lists 1 group name: Sanford Medical Center. See the list
Source: CMS Doctors and Clinicians National Downloadable File, CMS release of October 2, 2026.
Listings do not confirm current availability, employment or a shared ownership network.
Medicare Profile & Education
Source: CMS Doctors and Clinicians National Downloadable File, CMS release of October 2, 2026
2021
What Public CMS Data Show
Nurse Practitioner: NPPES taxonomy is a reported classification, not proof of board certification.
30-day fills
33 standardized 30-day fills in 2024
CMS converts prescriptions to 30-day supplies so they can be compared. A 90-day prescription counts as about three 30-day fills.
What this does not show: 30-day fills
It is not a count of patients and not a measure of quality.
Part D drug cost
$50 in 2024
The total cost of these prescriptions in 2024, paid by Medicare drug plans, patients and other payers together.
It shows the total spending on drugs this clinician prescribed, not what any one patient paid.
What this does not show: Part D drug cost
A higher cost often reflects the type of medicines a specialty uses. It is not your out-of-pocket cost and not a measure of quality.
Source: CMS, Medicare Part D Prescribers β by Provider and Drug, 2024.
Industry payments (Open Payments)
Fewer than 11 payment records totaling $23.11 in 2021
Drug and medical device companies must report certain payments to doctors and some other clinicians to CMS, such as meals, travel, speaking fees or research funding.
It shows reported financial ties between this clinician and companies. You can ask your clinician about them.
These records are submitted by drug and medical device companies, and a reported payment does not necessarily mean the financial relationship is improper.
General: payments not tied to research, such as meals, travel, consulting or speaking fees.
A reported payment does not necessarily mean the financial relationship is improper. Research payments can go to a hospital or university for a study the clinician leads, not to the clinician personally. Clinicians can dispute records with the company that reported them.
Source: CMS Open Payments, program year 2021.
Years since graduation
5 years (graduated 2021)
CMS Doctors and Clinicians data list 2021 as the year this clinician finished professional school.
It tells you roughly how long ago the clinician finished school.
What this does not show: Years since graduation
It is not the number of years in practice, and more years does not mean better care.
Source: CMS Doctors and Clinicians National Downloadable File, CMS release of October 2, 2026.
NPI first issued
2021
The year this clinician's National Provider Identifier (NPI) was issued. An NPI is a unique 10-digit ID that US health care providers use for billing.
What this does not show: NPI first issued
NPIs have been issued only since 2005, so this year is not necessarily when the clinician started practicing.
Source: CMS NPPES NPI Registry.
Accepts Medicare assignment
CMS data list this clinician as accepting Medicare assignment. This means agreeing to take the Medicare-approved amount as full payment for covered services.
With Original Medicare, you usually pay only your deductible and coinsurance, and the office sends the claim to Medicare for you.
Medicare assignment applies to Original Medicare. It does not tell you whether the clinician is in a Medicare Advantage plan's network, accepts other insurance, or is taking new patients.
Source: CMS Doctors and Clinicians, CMS release of October 2, 2026; Medicare.gov, βDoes your provider accept Medicare as full payment?β
No telehealth indicator
CMS shows this indicator only when recent Medicare claims include telehealth services. The clinician may still offer telehealth; ask the office.
Source: CMS, Telehealth Indicator on Medicare Care Compare (fact sheet, January 2023); CMS Doctors and Clinicians, CMS release of October 2, 2026.
Enrolled in Medicare (PECOS)
Danielle Karber has a Medicare enrollment record in PECOS, the CMS system clinicians use to enroll so they can bill Medicare or order services for people with Medicare.
It does not show whether the clinician accepts assignment, is in your plan's network, or is taking new patients.
Source: CMS Medicare Fee-For-Service Public Provider Enrollment (PECOS); CMS Order and Referring file.
Can order Medicare-covered services
CMS lists Danielle Karber as eligible to order or refer Medicare Part B clinical laboratory and imaging services, durable medical equipment (DME) and home health services for people with Medicare.
Medicare pays for these items and services only when they are ordered by an eligible clinician.
What this does not show: Can order Medicare-covered services
It does not mean the clinician offers these services directly.
Source: CMS Medicare Fee-For-Service Public Provider Enrollment (PECOS); CMS Order and Referring file.
Compared with the same specialty in Sioux Falls and South Dakota
Billing and prescribing volume is not a quality rating.
Medicare Part D prescriptions
Fewer Part D prescriptions than 95% of clinicians listed under Nurse Practitioner in Sioux Falls, SD (2024, 143 clinicians with data). Median for this group: 359. Middle half: 68 to 1,118.
Fewer Part D prescriptions than 95% of clinicians listed under Nurse Practitioner in South Dakota (2024, 285 clinicians with data). Median for this group: 349. Middle half: 78 to 1,193.
Part D drug cost
A lower Part D drug cost than 95% of clinicians listed under Nurse Practitioner in Sioux Falls, SD (2024, 143 clinicians with data). Median for this group: $36,319. Middle half: $728 to $183,185.
A lower Part D drug cost than 95% of clinicians listed under Nurse Practitioner in South Dakota (2024, 285 clinicians with data). Median for this group: $22,273. Middle half: $876 to $171,669.
245 active clinicians are listed under Nurse Practitioner with a practice address in Sioux Falls, SD (476 in South Dakota).
Addresses are self-reported to NPPES and may be out of date.
Telehealth indicator in Sioux Falls
17.6% of these 245 clinicians have the CMS telehealth indicator.
69% of these 245 clinicians are listed by CMS as accepting Medicare assignment.
CMS data by year
Changes may reflect reporting, coverage or privacy limits, not changes in care quality.
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Medicare Part D prescriptions
Medicare Part D prescriptions went from 11 in 2022 to 11 in 2024.
- 2022: 11
- 2024: 11
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30-day fills
30-day fills went from 13 in 2022 to 33 in 2024.
- 2022: 13
- 2024: 33
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Part D drug cost
Part D drug cost went from $142 in 2022 to $50 in 2024.
- 2022: $142
- 2024: $50
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Industry payments (Open Payments)
CMS data for industry payments (Open Payments) are available for 2021 only.
Sources: CMS Medicare Part D Prescribers (2024), CMS Open Payments (2021), CMS Doctors and Clinicians, CMS release of October 2, 2026, CMS NPPES NPI Registry. Specialty names follow the NUCC Health Care Provider Taxonomy.
Text: T-MedInfo Β· Report an error.
Pharma & Medical Device Financial Disclosures
Payments and other transfers of value that drug and medical device companies reported to CMS Open Payments
Program year 2021 (payments made January 1 β December 31, 2021): fewer than 11 records totaling $23.11.
| Manufacturer | Payment Nature | Product | Type | Amount ($) |
|---|---|---|---|---|
| Janssen Pharmaceuticals, Inc |
Food and Beverage
In-kind items and services
|
UPTRAVI | General | $23.11 |
Source: CMS Open Payments, program year 2021, released June 30, 2026.
Medicare Part D Prescribing Profile & Medications
Medicare Part D prescriptions filled, including refills, in 2024.
| Brand Name | Generic Name | Prescriptions | Day Supply | Total Cost | Patients |
|---|---|---|---|---|---|
| Lisinopril | Lisinopril | 11 | 990 | $49.91 | β |
Source: CMS Part D by Provider and Drug, 2024; rows below 11 claims omitted by CMS; volume isn’t quality. Privacy limits
Specialties & License Numbers Reported to NPPES
Self-certified to NPPES: 2026-11-02NUCC Taxonomy Code: 363L00000X
(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision making and direct accountability for clinical judgment across the health care continuum or in a certified specialty. (2) A registered nurse who has completed additional training beyond basic nursing education and who provides primary health care services in accordance with state nurse practice laws or statutes. Tasks performed by nurse practitioners vary with practice requirements mandated by geographic, political, economic, and social factors. Nurse practitioner specialists include, but are not limited to, family nurse practitioners, gerontological nurse practitioners, pediatric nurse practitioners, obstetric-gynecologic nurse practitioners, and school nurse practitioners.
NUCC Taxonomy Code: 163WP2201X
NUCC Taxonomy Code: 363LP2300X
Medicare (PECOS) Enrollment & Ordering Eligibility
Source: CMS PECOSPRACTITIONER - NURSE PRACTITIONER
I20260701003462
SD
4385118207
Sources: CMS Provider Enrollment and Order and Referring. Medicare enrollment is a billing status, not an accreditation or quality rating.
Medicare Group Practice Enrollments
Source: CMS Doctors and Clinicians National Downloadable File, CMS release of October 2, 2026
Sanford Medical Center
1301 W 18th St, Sioux Falls, SD 571050401
Phone: 6053122200
Sanford Medical Center
1305 W 18th St, Sioux Falls, SD 571050401
Sanford Medical Center
4405 E 26th St, Sioux Falls, SD 571034187
Secondary Practice Locations
2501 W 22nd St
Sioux Falls, SD 571051305
Phone: 6053363230
901 4th St Nw
Watertown, SD 572011558
Phone: 6058868471
300 S Byron Blvd
Chamberlain, SD 573259741
Phone: 6052346551
Clinicians Sharing This Practice Address or Phone
Clinicians sharing this NPPES address, phone or fax; a shared contact does not mean they work together.
Nurse Practitioner - Family
Certified Nurse Practitioner
Nurse Practitioner
MSNACNP
Nurse Practitioner
Physician Assistant
Physician Assistant (Certified)
Physician Assistant
Physician Assistant
Nurse Practitioner
Doctor of Nursing Practice, Nurse Practitioner (Certified)
Career & Practice History Timeline
Changes recorded in monthly NPPES data files: addresses, names, credentials, specialties and NPI status
Additional practice office at 901 4th St NW, Watertown, SD 572011558
Additional practice office at 300 S Byron Blvd, Chamberlain, SD 573259741
Registered at 1301 W 18TH ST, SIOUX FALLS, SD 571050401 (Tel: 6053122200)
Registered at PO BOX 5074, SIOUX FALLS, SD 571175074 (Tel: 6053286585)
Additional practice office at 2501 W 22nd St, Sioux Falls, SD 571051305
Registered Nurse (license number reported to NPPES: SD R041376)
NPI status registered as active in NPPES database
Registered at 2501 W 22ND ST, SIOUX FALLS, SD 571051305 (Tel: 6053363230)
Registered at 8909 W DRAGONFLY DR, SIOUX FALLS, SD 571073043
Recorded as DANIELLE KARBER, CNP
Nurse Practitioner (license number reported to NPPES: SD CP002138)
First registered as active Individual Practitioner in NPPES Database.
NPI Administrative Meta
Other Nurse Practitioners in Sioux Falls
- Nancy Foss, CNP
- Zachary Meyer, CNP
- Lisa Duncan, CNP
- Heather Johnson, CNP
- Betsy Rentschler, NP
- Heather Casper-Mclay, NP
Mailing Address
Po Box 5074
Sioux Falls, SD 571175074
Phone: 6053286585